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Significance of Thymosin β4 and Implication of PINCH-1-ILK-α-Parvin (PIP) Complex in Human Dilated Cardiomyopathy
Myocardial remodeling is a major contributor in the development of heart failure (HF) after myocardial infarction (MI). Integrin-linked kinase (ILK), LIM-only adaptor PINCH-1, and α-parvin are essential components of focal adhesions (FAs), which are highly expressed in the heart. ILK binds tightly t...
Autores principales: | Sopko, Nikolai, Qin, Yilu, Finan, Amanda, Dadabayev, Alisher, Chigurupati, Sravanthi, Qin, Jun, Penn, Marc S., Gupta, Sudhiranjan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098280/ https://www.ncbi.nlm.nih.gov/pubmed/21625516 http://dx.doi.org/10.1371/journal.pone.0020184 |
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