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Var2CSA Minimal CSA Binding Region Is Located within the N-Terminal Region

Var2CSA, a key molecule linked with pregnancy-associated malaria (PAM), causes sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by adhesion to chondroitin sulfate A (CSA). Var2CSA possesses a 300 kDa extracellular region composed of six Duffy-binding like (DBL) doma...

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Detalles Bibliográficos
Autores principales: Srivastava, Anand, Gangnard, Stéphane, Dechavanne, Sébastien, Amirat, Farroudja, Lewit Bentley, Anita, Bentley, Graham A., Gamain, Benoît
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098292/
https://www.ncbi.nlm.nih.gov/pubmed/21625526
http://dx.doi.org/10.1371/journal.pone.0020270