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CpG Islands Recruit a Histone H3 Lysine 36 Demethylase

In higher eukaryotes, up to 70% of genes have high levels of nonmethylated cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units. These features, called CpG islands, were identified over 20 years ago, but there remains little mechanistic evidence to suggest how these eni...

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Detalles Bibliográficos
Autores principales: Blackledge, Neil P., Zhou, Jin C., Tolstorukov, Michael Y., Farcas, Anca M., Park, Peter J., Klose, Robert J.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098377/
https://www.ncbi.nlm.nih.gov/pubmed/20417597
http://dx.doi.org/10.1016/j.molcel.2010.04.009