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CpG Islands Recruit a Histone H3 Lysine 36 Demethylase
In higher eukaryotes, up to 70% of genes have high levels of nonmethylated cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units. These features, called CpG islands, were identified over 20 years ago, but there remains little mechanistic evidence to suggest how these eni...
Autores principales: | Blackledge, Neil P., Zhou, Jin C., Tolstorukov, Michael Y., Farcas, Anca M., Park, Peter J., Klose, Robert J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098377/ https://www.ncbi.nlm.nih.gov/pubmed/20417597 http://dx.doi.org/10.1016/j.molcel.2010.04.009 |
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