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Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat

We have recently reported the importance of spinal rapamycin-sensitive pathways in maintaining persistent pain-like states. A descending facilitatory drive mediated through spinal 5-HT3 receptors (5-HT3Rs) originating from superficial dorsal horn NK1-expressing neurons and that relays through the pa...

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Detalles Bibliográficos
Autores principales: Asante, Curtis O., Dickenson, Anthony H.
Formato: Texto
Lenguaje:English
Publicado: Elsevier Scientific Publishers Ireland 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098387/
https://www.ncbi.nlm.nih.gov/pubmed/20709148
http://dx.doi.org/10.1016/j.neulet.2010.08.024