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Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat
We have recently reported the importance of spinal rapamycin-sensitive pathways in maintaining persistent pain-like states. A descending facilitatory drive mediated through spinal 5-HT3 receptors (5-HT3Rs) originating from superficial dorsal horn NK1-expressing neurons and that relays through the pa...
Autores principales: | Asante, Curtis O., Dickenson, Anthony H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier Scientific Publishers Ireland
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098387/ https://www.ncbi.nlm.nih.gov/pubmed/20709148 http://dx.doi.org/10.1016/j.neulet.2010.08.024 |
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