Carnauba wax nanoparticles enhance strong systemic and mucosal cellular and humoral immune responses to HIV-gp140 antigen

Induction of humoral responses to HIV at mucosal compartments without inflammation is important for vaccine design. We developed charged wax nanoparticles that efficiently adsorb protein antigens and are internalized by DC in the absence of inflammation. HIV-gp140-adsorbed nanoparticles induced stro...

Descripción completa

Detalles Bibliográficos
Autores principales: Arias, Mauricio A., Loxley, Andrew, Eatmon, Christy, Van Roey, Griet, Fairhurst, David, Mitchnick, Mark, Dash, Philip, Cole, Tom, Wegmann, Frank, Sattentau, Quentin, Shattock, Robin
Formato: Texto
Lenguaje:English
Publicado: Elsevier Science 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098439/
https://www.ncbi.nlm.nih.gov/pubmed/21145913
http://dx.doi.org/10.1016/j.vaccine.2010.11.084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098439/
https://www.ncbi.nlm.nih.gov/pubmed/21145913
http://dx.doi.org/10.1016/j.vaccine.2010.11.084

Ejemplares similares