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HIV-1 Modulates the tRNA Pool to Improve Translation Efficiency

Despite its poorly adapted codon usage, HIV-1 replicates and is expressed extremely well in human host cells. HIV-1 has recently been shown to package non-lysyl transfer RNAs (tRNAs) in addition to the tRNA(Lys) needed for priming reverse transcription and integration of the HIV-1 genome. By compari...

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Detalles Bibliográficos
Autores principales: van Weringh, Anna, Ragonnet-Cronin, Manon, Pranckeviciene, Erinija, Pavon-Eternod, Mariana, Kleiman, Lawrence, Xia, Xuhua
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098512/
https://www.ncbi.nlm.nih.gov/pubmed/21216840
http://dx.doi.org/10.1093/molbev/msr005