A comparison of multiple shRNA expression methods for combinatorial RNAi

RNAi gene therapies for HIV-1 will likely need to employ multiple shRNAs to counter resistant strains. We evaluated 3 shRNA co-expression methods to determine their suitability for present use; multiple expression vectors, multiple expression cassettes and single transcripts comprised of several dsR...

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Detalles Bibliográficos
Autores principales: Mcintyre, Glen J, Arndt, Allison J, Gillespie, Kirsten M, Mak, Wendy M, Fanning, Gregory C
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098768/
https://www.ncbi.nlm.nih.gov/pubmed/21496330
http://dx.doi.org/10.1186/1479-0556-9-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098768/
https://www.ncbi.nlm.nih.gov/pubmed/21496330
http://dx.doi.org/10.1186/1479-0556-9-9

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