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A comparison of multiple shRNA expression methods for combinatorial RNAi
RNAi gene therapies for HIV-1 will likely need to employ multiple shRNAs to counter resistant strains. We evaluated 3 shRNA co-expression methods to determine their suitability for present use; multiple expression vectors, multiple expression cassettes and single transcripts comprised of several dsR...
Huvudupphovsmän: | , , , , |
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Materialtyp: | Text |
Språk: | English |
Publicerad: |
BioMed Central
2011
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Ämnen: | |
Länkar: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098768/ https://www.ncbi.nlm.nih.gov/pubmed/21496330 http://dx.doi.org/10.1186/1479-0556-9-9 |