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TGF-β Suppresses β-Catenin-Dependent Tolerogenic Activation Program in Dendritic Cells

The mechanisms that underlie the critical dendritic cell (DC) function in maintainance of peripheral immune tolerance are incompletely understood, although the β-catenin signaling pathway is critical for this role. The molecular details by which β-catenin signaling is regulated in DCs are unknown. M...

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Detalles Bibliográficos
Autores principales: Vander Lugt, Bryan, Beck, Zachary T., Fuhlbrigge, Robert C., Hacohen, Nir, Campbell, James J., Boes, Marianne
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098869/
https://www.ncbi.nlm.nih.gov/pubmed/21625453
http://dx.doi.org/10.1371/journal.pone.0020099