Cargando…
Continuum Molecular Simulation of Large Conformational Changes during Ion–Channel Gating
A modeling framework was developed to simulate large and gradual conformational changes within a macromolecule (protein) when its low amplitude high frequency vibrations are not concerned. Governing equations were derived as alternative to Langevin and Smoluchowski equations and used to simulate gat...
| Autores principales: | , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098872/ https://www.ncbi.nlm.nih.gov/pubmed/21625456 http://dx.doi.org/10.1371/journal.pone.0020186 |