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Whole-Genome Immunoinformatic Analysis of F. tularensis: Predicted CTL Epitopes Clustered in Hotspots Are Prone to Elicit a T-Cell Response

The cellular arm of the immune response plays a central role in the defense against intracellular pathogens, such as F. tularensis. To date, whole genome immunoinformatic analyses were limited either to relatively small genomes (e.g. viral) or to preselected subsets of proteins in complex pathogens....

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Detalles Bibliográficos
Autores principales: Zvi, Anat, Rotem, Shahar, Bar-Haim, Erez, Cohen, Ofer, Shafferman, Avigdor
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098878/
https://www.ncbi.nlm.nih.gov/pubmed/21625462
http://dx.doi.org/10.1371/journal.pone.0020050