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Whole-Genome Immunoinformatic Analysis of F. tularensis: Predicted CTL Epitopes Clustered in Hotspots Are Prone to Elicit a T-Cell Response
The cellular arm of the immune response plays a central role in the defense against intracellular pathogens, such as F. tularensis. To date, whole genome immunoinformatic analyses were limited either to relatively small genomes (e.g. viral) or to preselected subsets of proteins in complex pathogens....
Autores principales: | Zvi, Anat, Rotem, Shahar, Bar-Haim, Erez, Cohen, Ofer, Shafferman, Avigdor |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098878/ https://www.ncbi.nlm.nih.gov/pubmed/21625462 http://dx.doi.org/10.1371/journal.pone.0020050 |
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