Unfaithful Maintenance of Methylation Imprints Due to Loss of Maternal Nuclear Dnmt1 during Somatic Cell Nuclear Transfer

The low success rate of somatic cell nuclear transfer (SCNT) in mammalian cloning is largely due to imprinting problems. However, little is known about the mechanisms of reprogramming imprinted genes during SCNT. Parental origin-specific DNA methylation regulates the monoallelic expression of imprin...

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Detalles Bibliográficos
Autores principales: Wei, Yanchang, Huan, Yanjun, Shi, Yongqian, Liu, Zhongfeng, Bou, Gerelchimeg, Luo, Yibo, Zhang, Li, Yang, Cairong, Kong, Qingran, Tian, Jiangtian, Xia, Ping, Sun, Qing-Yuan, Liu, ZhongHua
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098883/
https://www.ncbi.nlm.nih.gov/pubmed/21625467
http://dx.doi.org/10.1371/journal.pone.0020154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098883/
https://www.ncbi.nlm.nih.gov/pubmed/21625467
http://dx.doi.org/10.1371/journal.pone.0020154

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