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Buffering and the evolution of chromosome-wide gene regulation
Copy number variation (CNV) in terms of aneuploidies of both entire chromosomes and chromosomal segments is an important evolutionary driving force, but it is inevitably accompanied by potentially problematic variations in gene doses and genomic instability. Thus, a delicate balance must be maintain...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098985/ https://www.ncbi.nlm.nih.gov/pubmed/21505791 http://dx.doi.org/10.1007/s00412-011-0319-8 |