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Buffering and the evolution of chromosome-wide gene regulation

Copy number variation (CNV) in terms of aneuploidies of both entire chromosomes and chromosomal segments is an important evolutionary driving force, but it is inevitably accompanied by potentially problematic variations in gene doses and genomic instability. Thus, a delicate balance must be maintain...

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Detalles Bibliográficos
Autores principales: Stenberg, Per, Larsson, Jan
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3098985/
https://www.ncbi.nlm.nih.gov/pubmed/21505791
http://dx.doi.org/10.1007/s00412-011-0319-8