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The Interplay between NF-kappaB and E2F1 Coordinately Regulates Inflammation and Metabolism in Human Cardiac Cells

Pyruvate dehydrogenase kinase 4 (PDK4) inhibition by nuclear factor-κB (NF-κB) is related to a shift towards increased glycolysis during cardiac pathological processes such as cardiac hypertrophy and heart failure. The transcription factors estrogen-related receptor-α (ERRα) and peroxisome prolifera...

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Detalles Bibliográficos
Autores principales: Palomer, Xavier, Álvarez-Guardia, David, Davidson, Mercy M., Chan, Tung O., Feldman, Arthur M., Vázquez-Carrera, Manuel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100304/
https://www.ncbi.nlm.nih.gov/pubmed/21625432
http://dx.doi.org/10.1371/journal.pone.0019724