Intermittent Hypoxia-Induced Cognitive Deficits Are Mediated by NADPH Oxidase Activity in a Murine Model of Sleep Apnea

BACKGROUND: In rodents, exposure to intermittent hypoxia (IH), a hallmark of obstructive sleep apnea (OSA), is associated with neurobehavioral impairments, increased apoptosis in the hippocampus and cortex, as well as increased oxidant stress and inflammation. Excessive NADPH oxidase activity may pl...

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Detalles Bibliográficos
Autores principales: Nair, Deepti, Dayyat, Ehab A., Zhang, Shelley X., Wang, Yang, Gozal, David
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100309/
https://www.ncbi.nlm.nih.gov/pubmed/21625437
http://dx.doi.org/10.1371/journal.pone.0019847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100309/
https://www.ncbi.nlm.nih.gov/pubmed/21625437
http://dx.doi.org/10.1371/journal.pone.0019847

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