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Glioblastoma Models Reveal the Connection between Adult Glial Progenitors and the Proneural Phenotype

BACKGROUND: Tumor heterogeneity is a major obstacle for finding effective treatment of Glioblastoma (GBM). Based on global expression analysis, GBM can be classified into distinct subtypes: Proneural, Neural, Classical and Mesenchymal. The signatures of these different tumor subtypes may reflect the...

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Detalles Bibliográficos
Autores principales: Lei, Liang, Sonabend, Adam M., Guarnieri, Paolo, Soderquist, Craig, Ludwig, Thomas, Rosenfeld, Steven, Bruce, Jeffrey N., Canoll, Peter
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100315/
https://www.ncbi.nlm.nih.gov/pubmed/21625383
http://dx.doi.org/10.1371/journal.pone.0020041