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Lack of the Receptor for Advanced Glycation End-Products Attenuates E. coli Pneumonia in Mice

BACKGROUND: The receptor for advanced glycation end-products (RAGE) has been suggested to modulate lung injury in models of acute pulmonary inflammation. To study this further, model systems utilizing wild type and RAGE knockout (KO) mice were used to determine the role of RAGE signaling in lipopoly...

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Detalles Bibliográficos
Autores principales: Ramsgaard, Lasse, Englert, Judson M., Manni, Michelle L., Milutinovic, Pavle S., Gefter, Julia, Tobolewski, Jacob, Crum, Lauren, Coudriet, Gina M., Piganelli, Jon, Zamora, Ruben, Vodovotz, Yoram, Enghild, Jan J., Oury, Tim D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100338/
https://www.ncbi.nlm.nih.gov/pubmed/21629785
http://dx.doi.org/10.1371/journal.pone.0020132