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Lack of the Receptor for Advanced Glycation End-Products Attenuates E. coli Pneumonia in Mice
BACKGROUND: The receptor for advanced glycation end-products (RAGE) has been suggested to modulate lung injury in models of acute pulmonary inflammation. To study this further, model systems utilizing wild type and RAGE knockout (KO) mice were used to determine the role of RAGE signaling in lipopoly...
Autores principales: | Ramsgaard, Lasse, Englert, Judson M., Manni, Michelle L., Milutinovic, Pavle S., Gefter, Julia, Tobolewski, Jacob, Crum, Lauren, Coudriet, Gina M., Piganelli, Jon, Zamora, Ruben, Vodovotz, Yoram, Enghild, Jan J., Oury, Tim D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100338/ https://www.ncbi.nlm.nih.gov/pubmed/21629785 http://dx.doi.org/10.1371/journal.pone.0020132 |
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