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Concentration Independent Modulation of Local Micromechanics in a Fibrin Gel
Methods for tuning extracellular matrix (ECM) mechanics in 3D cell culture that rely on increasing the concentration of either protein or cross-linking molecules fail to control important parameters such as pore size, ligand density, and molecular diffusivity. Alternatively, ECM stiffness can be mod...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100350/ https://www.ncbi.nlm.nih.gov/pubmed/21629793 http://dx.doi.org/10.1371/journal.pone.0020201 |