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Concentration Independent Modulation of Local Micromechanics in a Fibrin Gel

Methods for tuning extracellular matrix (ECM) mechanics in 3D cell culture that rely on increasing the concentration of either protein or cross-linking molecules fail to control important parameters such as pore size, ligand density, and molecular diffusivity. Alternatively, ECM stiffness can be mod...

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Detalles Bibliográficos
Autores principales: Kotlarchyk, Maxwell A., Shreim, Samir G., Alvarez-Elizondo, Martha B., Estrada, Laura C., Singh, Rahul, Valdevit, Lorenzo, Kniazeva, Ekaterina, Gratton, Enrico, Putnam, Andrew J., Botvinick, Elliot L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100350/
https://www.ncbi.nlm.nih.gov/pubmed/21629793
http://dx.doi.org/10.1371/journal.pone.0020201