Self-Renewal Signalling in Presenescent Tetraploid IMR90 Cells

Endopolyploidy and genomic instability are shared features of both stress-induced cellular senescence and malignant growth. Here, we examined these facets in the widely used normal human fibroblast model of senescence, IMR90. At the presenescence stage, a small (2–7%) proportion of cells overcome th...

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Detalles Bibliográficos
Autores principales: Huna, Anda, Salmina, Kristine, Jascenko, Elina, Duburs, Gunars, Inashkina, Inna, Erenpreisa, Jekaterina
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100543/
https://www.ncbi.nlm.nih.gov/pubmed/21629737
http://dx.doi.org/10.4061/2011/103253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100543/
https://www.ncbi.nlm.nih.gov/pubmed/21629737
http://dx.doi.org/10.4061/2011/103253

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