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Autophagic and Apoptotic Effects of HDAC Inhibitors on Cancer Cells

Because epigenetic alterations are believed to be involved in the repression of tumor suppressor genes and the promotion of tumorigenesis in cancers, novel compounds endowed with histone deacetylase (HDAC) inhibitory activity are an attractive therapeutic approach. Indeed, the potential of HDAC inhi...

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Detalles Bibliográficos
Autor principal: Rikiishi, Hidemi
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100649/
https://www.ncbi.nlm.nih.gov/pubmed/21629704
http://dx.doi.org/10.1155/2011/830260