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Computer-Based De Novo Designs of Tripeptides as Novel Neuraminidase Inhibitors

The latest influenza A (H1N1) pandemic attracted worldwide attention and called for the urgent development of novel antiviral drugs. Here, seven tripeptides are designed and explored as neuraminidase (NA) inhibitors on the structural basis of known inhibitors. Their interactions with NA are studied...

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Detalles Bibliográficos
Autores principales: Yang, Zhiwei, Yang, Gang, Zu, Yuangang, Fu, Yujie, Zhou, Lijun
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100827/
https://www.ncbi.nlm.nih.gov/pubmed/21614183
http://dx.doi.org/10.3390/ijms11124932