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Antiproliferative Effects of Cucurbitacin B in Breast Cancer Cells: Down-Regulation of the c-Myc/hTERT/Telomerase Pathway and Obstruction of the Cell Cycle

Naturally occurring cucurbitacins have been shown to have anticancer, antimicrobial and anti-inflammatory activities. In this study, we determined the effects of cucurbitacin B extracted from the Thai herb Trichosanthes cucumerina L. on telomerase regulation in three human breast cancer cell lines (...

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Detalles Bibliográficos
Autores principales: Duangmano, Suwit, Dakeng, Sumana, Jiratchariyakul, Weena, Suksamrarn, Apichart, Smith, Duncan R., Patmasiriwat, Pimpicha
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100835/
https://www.ncbi.nlm.nih.gov/pubmed/21614210
http://dx.doi.org/10.3390/ijms11125323