Replication protein A safeguards genome integrity by controlling NER incision events

Single-stranded DNA gaps that might arise by futile repair processes can lead to mutagenic events and challenge genome integrity. Nucleotide excision repair (NER) is an evolutionarily conserved repair mechanism, essential for removal of helix-distorting DNA lesions. In the currently prevailing model...

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Detalles Bibliográficos
Autores principales: Overmeer, René M., Moser, Jill, Volker, Marcel, Kool, Hanneke, Tomkinson, Alan E., van Zeeland, Albert A., Mullenders, Leon H.F., Fousteri, Maria
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101093/
https://www.ncbi.nlm.nih.gov/pubmed/21282463
http://dx.doi.org/10.1083/jcb.201006011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101093/
https://www.ncbi.nlm.nih.gov/pubmed/21282463
http://dx.doi.org/10.1083/jcb.201006011

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