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The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell–ECM signaling

The serine/threonine kinase Par1b promotes cell–cell adhesion and determines the polarity of the luminal domain in epithelial cells. In this study, we demonstrate that Par1b also regulates cell–extracellular matrix (ECM) signaling in kidney-derived Madin–Darby canine kidney (MDCK) cells and identifi...

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Detalles Bibliográficos
Autores principales: Cohen, David, Fernandez, Dawn, Lázaro-Diéguez, Francisco, Müsch, Anne
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101094/
https://www.ncbi.nlm.nih.gov/pubmed/21282462
http://dx.doi.org/10.1083/jcb.201007002