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The serine/threonine kinase Par1b regulates epithelial lumen polarity via IRSp53-mediated cell–ECM signaling
The serine/threonine kinase Par1b promotes cell–cell adhesion and determines the polarity of the luminal domain in epithelial cells. In this study, we demonstrate that Par1b also regulates cell–extracellular matrix (ECM) signaling in kidney-derived Madin–Darby canine kidney (MDCK) cells and identifi...
Autores principales: | Cohen, David, Fernandez, Dawn, Lázaro-Diéguez, Francisco, Müsch, Anne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101094/ https://www.ncbi.nlm.nih.gov/pubmed/21282462 http://dx.doi.org/10.1083/jcb.201007002 |
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