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The full-of-bacteria gene is required for phagosome maturation during immune defense in Drosophila

Arthrogryposis, renal dysfunction, and cholestasis (ARC) syndrome is a fatal recessive disorder caused by mutations in the VPS33B or VPS16B genes. Both encode homologues of the Vps33p and Vps16p subunits of the HOPS complex necessary for fusions of vacuoles in yeast. Here, we describe a mutation in...

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Detalles Bibliográficos
Autores principales: Akbar, Mohammed Ali, Tracy, Charles, Kahr, Walter H.A., Krämer, Helmut
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101095/
https://www.ncbi.nlm.nih.gov/pubmed/21282466
http://dx.doi.org/10.1083/jcb.201008119