The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas

CD40, a tumor necrosis factor (TNF) receptor family member, is widely recognized for its prominent role in the antitumor immune response. The immunostimulatory effects of CD40 ligation on malignant cells can be switched to apoptosis upon disruption of survival signals transduced by the binding of th...

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Detalles Bibliográficos
Autores principales: Knox, Pauline G., Davies, Clare C., Ioannou, Marina, Eliopoulos, Aristides G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101101/
https://www.ncbi.nlm.nih.gov/pubmed/21282461
http://dx.doi.org/10.1083/jcb.201003087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101101/
https://www.ncbi.nlm.nih.gov/pubmed/21282461
http://dx.doi.org/10.1083/jcb.201003087

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