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The death domain kinase RIP1 links the immunoregulatory CD40 receptor to apoptotic signaling in carcinomas
CD40, a tumor necrosis factor (TNF) receptor family member, is widely recognized for its prominent role in the antitumor immune response. The immunostimulatory effects of CD40 ligation on malignant cells can be switched to apoptosis upon disruption of survival signals transduced by the binding of th...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101101/ https://www.ncbi.nlm.nih.gov/pubmed/21282461 http://dx.doi.org/10.1083/jcb.201003087 |