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Randomized controlled phase I/II study to investigate immune stimulatory effects by low dose radiotherapy in primarily operable pancreatic cancer

BACKGROUND: The efficiencies of T cell based immunotherapies are affected by insufficient migration and activation of tumor specific effector T cells in the tumor. Accumulating evidence exists on the ability of ionizing radiation to modify the tumor microenvironment and generate inflammation. The ai...

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Detalles Bibliográficos
Autores principales: Timke, Carmen, Winnenthal, Hubertus Schmitz, Klug, Felix, Roeder, Falk FF, Bonertz, Andreas, Reissfelder, Christoph, Rochet, Nathalie, Koch, Moritz, Tjaden, Christine, Buechler, Markus W, Debus, Juergen, Werner, Jens, Beckhove, Philipp, Weitz, Jürgen, Huber, Peter E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101175/
https://www.ncbi.nlm.nih.gov/pubmed/21489291
http://dx.doi.org/10.1186/1471-2407-11-134