Trapping Conformational States Along Ligand-Binding Dynamics of Peptide Deformylase: The Impact of Induced Fit on Enzyme Catalysis

For several decades, molecular recognition has been considered one of the most fundamental processes in biochemistry. For enzymes, substrate binding is often coupled to conformational changes that alter the local environment of the active site to align the reactive groups for efficient catalysis and...

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Detalles Bibliográficos
Autores principales: Fieulaine, Sonia, Boularot, Adrien, Artaud, Isabelle, Desmadril, Michel, Dardel, Frédéric, Meinnel, Thierry, Giglione, Carmela
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101196/
https://www.ncbi.nlm.nih.gov/pubmed/21629676
http://dx.doi.org/10.1371/journal.pbio.1001066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101196/
https://www.ncbi.nlm.nih.gov/pubmed/21629676
http://dx.doi.org/10.1371/journal.pbio.1001066

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