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Nucleolar Localization of RNA Binding Proteins Induced by Actinomycin D and Heat Shock in Trypanosoma cruzi

In this work we show that under Actinomycin D (ActD) treatment, several RNA Binding Proteins (RBPs) involved in mRNA metabolism are relocalized into the nucleolus in Trypanosoma cruzi as a specific stress response. ATP depletion as well as kinase inhibition markedly reduced the nucleolar localizatio...

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Detalles Bibliográficos
Autores principales: Názer, Ezequiel, Verdún, Ramiro E., Sánchez, Daniel O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101214/
https://www.ncbi.nlm.nih.gov/pubmed/21629693
http://dx.doi.org/10.1371/journal.pone.0019920