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Preclinical Development of an In Vivo BCG Challenge Model for Testing Candidate TB Vaccine Efficacy

There is an urgent need for an immunological correlate of protection against tuberculosis (TB) with which to evaluate candidate TB vaccines in clinical trials. Development of a human challenge model of Mycobacterium tuberculosis (M.tb) could facilitate the detection of such correlate(s). Here we pro...

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Detalles Bibliográficos
Autores principales: Minassian, Angela M., Ronan, Edward O., Poyntz, Hazel, Hill, Adrian V. S., McShane, Helen
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101220/
https://www.ncbi.nlm.nih.gov/pubmed/21629699
http://dx.doi.org/10.1371/journal.pone.0019840