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Preclinical Development of an In Vivo BCG Challenge Model for Testing Candidate TB Vaccine Efficacy
There is an urgent need for an immunological correlate of protection against tuberculosis (TB) with which to evaluate candidate TB vaccines in clinical trials. Development of a human challenge model of Mycobacterium tuberculosis (M.tb) could facilitate the detection of such correlate(s). Here we pro...
Autores principales: | Minassian, Angela M., Ronan, Edward O., Poyntz, Hazel, Hill, Adrian V. S., McShane, Helen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101220/ https://www.ncbi.nlm.nih.gov/pubmed/21629699 http://dx.doi.org/10.1371/journal.pone.0019840 |
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