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Production of Multiple Brain-Like Ganglioside Species Is Dispensable for Fas-Induced Apoptosis of Lymphoid Cells

Activation of an acid sphingomyelinase (aSMase) leading to a biosynthesis of GD3 disialoganglioside has been associated with Fas-induced apoptosis of lymphoid cells. The present study was undertaken to clarify the role of this enzyme in the generation of gangliosides during apoptosis triggered by Fa...

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Detalles Bibliográficos
Autores principales: Popa, Iuliana, Therville, Nicole, Carpentier, Stéphane, Levade, Thierry, Cuvillier, Olivier, Portoukalian, Jacques
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101221/
https://www.ncbi.nlm.nih.gov/pubmed/21629700
http://dx.doi.org/10.1371/journal.pone.0019974