Accelerated Neuronal Cell Recovery from Botulinum Neurotoxin Intoxication by Targeted Ubiquitination

Botulinum neurotoxin (BoNT), a Category A biodefense agent, delivers a protease to motor neuron cytosol that cleaves one or more soluble NSF attachment protein receptors (SNARE) proteins involved in neurotransmission to cause a flaccid paralysis. No antidotes exist to reverse symptoms of BoNT intoxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuo, Chueh-Ling, Oyler, George A., Shoemaker, Charles B.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101245/
https://www.ncbi.nlm.nih.gov/pubmed/21629663
http://dx.doi.org/10.1371/journal.pone.0020352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101245/
https://www.ncbi.nlm.nih.gov/pubmed/21629663
http://dx.doi.org/10.1371/journal.pone.0020352

Ejemplares similares