VPS29 Is Not an Active Metallo-Phosphatase but Is a Rigid Scaffold Required for Retromer Interaction with Accessory Proteins

VPS29 is a key component of the cargo-binding core complex of retromer, a protein assembly with diverse roles in transport of receptors within the endosomal system. VPS29 has a fold related to metal-binding phosphatases and mediates interactions between retromer and other regulatory proteins. In thi...

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Detalles Bibliográficos
Autores principales: Swarbrick, James D., Shaw, Daniel J., Chhabra, Sandeep, Ghai, Rajesh, Valkov, Eugene, Norwood, Suzanne J., Seaman, Matthew N. J., Collins, Brett M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101248/
https://www.ncbi.nlm.nih.gov/pubmed/21629666
http://dx.doi.org/10.1371/journal.pone.0020420

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101248/
https://www.ncbi.nlm.nih.gov/pubmed/21629666
http://dx.doi.org/10.1371/journal.pone.0020420

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