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VPS29 Is Not an Active Metallo-Phosphatase but Is a Rigid Scaffold Required for Retromer Interaction with Accessory Proteins
VPS29 is a key component of the cargo-binding core complex of retromer, a protein assembly with diverse roles in transport of receptors within the endosomal system. VPS29 has a fold related to metal-binding phosphatases and mediates interactions between retromer and other regulatory proteins. In thi...
Autores principales: | Swarbrick, James D., Shaw, Daniel J., Chhabra, Sandeep, Ghai, Rajesh, Valkov, Eugene, Norwood, Suzanne J., Seaman, Matthew N. J., Collins, Brett M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101248/ https://www.ncbi.nlm.nih.gov/pubmed/21629666 http://dx.doi.org/10.1371/journal.pone.0020420 |
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