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Interactions of the Melanocortin-4 Receptor with the Peptide Agonist NDP-MSH

Melanocortin-4 receptor (MC4R) has an important regulatory role in energy homeostasis and food intake. Peptide agonists of the MC4R are characterized by the conserved sequence His(6)-Phe(7)-Arg(8)-Trp(9), which is crucial for their interaction with the receptor. This investigation utilized the coval...

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Detalles Bibliográficos
Autores principales: Chapman, Kathryn L., Kinsella, Gemma K., Cox, Alan, Donnelly, Dan, Findlay, John B.C.
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101337/
https://www.ncbi.nlm.nih.gov/pubmed/20600126
http://dx.doi.org/10.1016/j.jmb.2010.06.028