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Interactions of the Melanocortin-4 Receptor with the Peptide Agonist NDP-MSH
Melanocortin-4 receptor (MC4R) has an important regulatory role in energy homeostasis and food intake. Peptide agonists of the MC4R are characterized by the conserved sequence His(6)-Phe(7)-Arg(8)-Trp(9), which is crucial for their interaction with the receptor. This investigation utilized the coval...
Autores principales: | Chapman, Kathryn L., Kinsella, Gemma K., Cox, Alan, Donnelly, Dan, Findlay, John B.C. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101337/ https://www.ncbi.nlm.nih.gov/pubmed/20600126 http://dx.doi.org/10.1016/j.jmb.2010.06.028 |
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