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De novo assembly of potential linear artificial chromosome constructs capped with expansive telomeric repeats

BACKGROUND: Artificial chromosomes (ACs) are a promising next-generation vector for genetic engineering. The most common methods for developing AC constructs are to clone and combine centromeric DNA and telomeric DNA fragments into a single large DNA construct. The AC constructs developed from such...

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Detalles Bibliográficos
Autores principales: Lin, Li, Koo, Dal-Hoe, Zhang, Wenli, St Peter, Joseph, Jiang, Jiming
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101654/
https://www.ncbi.nlm.nih.gov/pubmed/21496260
http://dx.doi.org/10.1186/1746-4811-7-10