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De novo assembly of potential linear artificial chromosome constructs capped with expansive telomeric repeats
BACKGROUND: Artificial chromosomes (ACs) are a promising next-generation vector for genetic engineering. The most common methods for developing AC constructs are to clone and combine centromeric DNA and telomeric DNA fragments into a single large DNA construct. The AC constructs developed from such...
Autores principales: | Lin, Li, Koo, Dal-Hoe, Zhang, Wenli, St Peter, Joseph, Jiang, Jiming |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101654/ https://www.ncbi.nlm.nih.gov/pubmed/21496260 http://dx.doi.org/10.1186/1746-4811-7-10 |
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