S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism

The injurious consequences of ionizing radiation (IR) to normal human cells and the acquired radioresistance of cancer cells represent limitations to cancer radiotherapy. IR induces DNA damage response pathways that orchestrate cell cycle arrest, DNA repair or apoptosis such that irradiated cells ar...

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Detalles Bibliográficos
Autores principales: Kumar, A, Oskouian, B, Fyrst, H, Zhang, M, Paris, F, Saba, J D
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101703/
https://www.ncbi.nlm.nih.gov/pubmed/21368890
http://dx.doi.org/10.1038/cddis.2011.3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101703/
https://www.ncbi.nlm.nih.gov/pubmed/21368890
http://dx.doi.org/10.1038/cddis.2011.3

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