Frataxin participates to the hypoxia-induced response in tumors

Defective expression of frataxin is responsible for the degenerative disease Friedreich's ataxia. Frataxin is a protein required for cell survival since complete knockout is lethal. Frataxin protects tumor cells against oxidative stress and apoptosis but also acts as a tumor suppressor. The mol...

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Detalles Bibliográficos
Autores principales: Guccini, I, Serio, D, Condò, I, Rufini, A, Tomassini, B, Mangiola, A, Maira, G, Anile, C, Fina, D, Pallone, F, Mongiardi, M P, Levi, A, Ventura, N, Testi, R, Malisan, F
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101705/
https://www.ncbi.nlm.nih.gov/pubmed/21368894
http://dx.doi.org/10.1038/cddis.2011.5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101705/
https://www.ncbi.nlm.nih.gov/pubmed/21368894
http://dx.doi.org/10.1038/cddis.2011.5

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