Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia

PURPOSE: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia. METHODS...

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Autores principales: Ghali, Ashraf, Mahfouz, Abdul Kader, Ihanamäki, Tapio, El Btarny, Ashraf M.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101751/
https://www.ncbi.nlm.nih.gov/pubmed/21655014
http://dx.doi.org/10.4103/1658-354X.76506
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author Ghali, Ashraf
Mahfouz, Abdul Kader
Ihanamäki, Tapio
El Btarny, Ashraf M.
author_facet Ghali, Ashraf
Mahfouz, Abdul Kader
Ihanamäki, Tapio
El Btarny, Ashraf M.
author_sort Ghali, Ashraf
collection PubMed
description PURPOSE: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia. METHODS: Sixty patients were enrolled in this prospective, single-blind, randomized study. The patients were divided into two groups to receive either dexmedetomidine (group D) or propofol (group P). Sedation level was titrated to a Ramsay sedation scale (RSS) of 3. Hemodynamic and respiratory effects, postoperative recovery time, analgesic effects, surgeons and patients satisfaction were assessed. RESULTS: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values. The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group. The oxygen saturation values of the dexmedetomidine group were significantly higher than those of the propofol group. The expired CO(2) was similar in both groups. Postoperatively, the time to achieve an Aldrete score of 10 was similar in both groups. Dexmedetomidine patients have significantly lower visual analog scale for pain than propofol patients. The surgeon satisfaction with patients’ sedation was similar for both groups. The patients’ satisfaction was higher in the dexmedetomidine group. CONCLUSION: Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon’s satisfaction, and higher patient’s satisfaction. Thus, dexmedetomidine may prove to be a valuable adjuvant for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia.
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spelling pubmed-31017512011-06-08 Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia Ghali, Ashraf Mahfouz, Abdul Kader Ihanamäki, Tapio El Btarny, Ashraf M. Saudi J Anaesth Original Article PURPOSE: The purpose of this study was to evaluate the hemodynamic, respiratory effects, the recovery profile, surgeons, and patients satisfaction with dexmedetomidine sedation compared with those of propofol sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia. METHODS: Sixty patients were enrolled in this prospective, single-blind, randomized study. The patients were divided into two groups to receive either dexmedetomidine (group D) or propofol (group P). Sedation level was titrated to a Ramsay sedation scale (RSS) of 3. Hemodynamic and respiratory effects, postoperative recovery time, analgesic effects, surgeons and patients satisfaction were assessed. RESULTS: Both groups provided a similar significant reduction in heart rate and mean arterial pressure compared with baseline values. The respiratory rate values of the dexmedetomidine group were significantly higher than those in the propofol group. The oxygen saturation values of the dexmedetomidine group were significantly higher than those of the propofol group. The expired CO(2) was similar in both groups. Postoperatively, the time to achieve an Aldrete score of 10 was similar in both groups. Dexmedetomidine patients have significantly lower visual analog scale for pain than propofol patients. The surgeon satisfaction with patients’ sedation was similar for both groups. The patients’ satisfaction was higher in the dexmedetomidine group. CONCLUSION: Dexmedetomidine at similar sedation levels with propofol was associated with equivalent hemodynamic effects, maintaining an adequate respiratory function, similar time of discharge from PACU, better analgesic properties, similar surgeon’s satisfaction, and higher patient’s satisfaction. Thus, dexmedetomidine may prove to be a valuable adjuvant for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia. Medknow Publications 2011 /pmc/articles/PMC3101751/ /pubmed/21655014 http://dx.doi.org/10.4103/1658-354X.76506 Text en © Saudi Journal of Anaesthesia http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ghali, Ashraf
Mahfouz, Abdul Kader
Ihanamäki, Tapio
El Btarny, Ashraf M.
Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia
title Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia
title_full Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia
title_fullStr Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia
title_full_unstemmed Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia
title_short Dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-Tenon’s anesthesia
title_sort dexmedetomidine versus propofol for sedation in patients undergoing vitreoretinal surgery under sub-tenon’s anesthesia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101751/
https://www.ncbi.nlm.nih.gov/pubmed/21655014
http://dx.doi.org/10.4103/1658-354X.76506
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