Requirement of Replication Checkpoint Protein Kinases Mec1/Rad53 for Postreplication Repair in Yeast

DNA lesions in the template strand block the replication fork. In Saccharomyces cerevisiae, replication through DNA lesions occurs via a Rad6/Rad18-dependent pathway where lesions can be bypassed by the action of translesion synthesis (TLS) DNA polymerases η and ζ or by Rad5-mediated template switch...

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Detalles Bibliográficos
Autores principales: Gangavarapu, Venkateswarlu, Santa Maria, Sergio R., Prakash, Satya, Prakash, Louise
Formato: Texto
Lenguaje:English
Publicado: American Society of Microbiology 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101783/
https://www.ncbi.nlm.nih.gov/pubmed/21586645
http://dx.doi.org/10.1128/mBio.00079-11

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101783/
https://www.ncbi.nlm.nih.gov/pubmed/21586645
http://dx.doi.org/10.1128/mBio.00079-11

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