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Requirement of Replication Checkpoint Protein Kinases Mec1/Rad53 for Postreplication Repair in Yeast
DNA lesions in the template strand block the replication fork. In Saccharomyces cerevisiae, replication through DNA lesions occurs via a Rad6/Rad18-dependent pathway where lesions can be bypassed by the action of translesion synthesis (TLS) DNA polymerases η and ζ or by Rad5-mediated template switch...
Autores principales: | Gangavarapu, Venkateswarlu, Santa Maria, Sergio R., Prakash, Satya, Prakash, Louise |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101783/ https://www.ncbi.nlm.nih.gov/pubmed/21586645 http://dx.doi.org/10.1128/mBio.00079-11 |
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