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Enhanced neuronal Met signalling levels in ALS mice delay disease onset

Signalling by receptor tyrosine kinases (RTKs) coordinates basic cellular processes during development and in adulthood. Whereas aberrant RTK signalling can lead to cancer, reactivation of RTKs is often found following stress or cell damage. This has led to the common belief that RTKs can counteract...

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Detalles Bibliográficos
Autores principales: Genestine, M, Caricati, E, Fico, A, Richelme, S, Hassani, H, Sunyach, C, Lamballe, F, Panzica, G C, Pettmann, B, Helmbacher, F, Raoul, C, Maina, F, Dono, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3101808/
https://www.ncbi.nlm.nih.gov/pubmed/21412276
http://dx.doi.org/10.1038/cddis.2011.11